Association of severe and therapy-refractory systemic lupus erythematosus and neuromyelitis optica: a management challen

In this category you will have access to a database containing journal articles in the form of abstracts and full journal articles.
Post Reply
HSowalla
Forum Admin
Forum Admin
Posts: 25
Joined: Sat Sep 02, 2017 11:24 pm

Association of severe and therapy-refractory systemic lupus erythematosus and neuromyelitis optica: a management challen

Post by HSowalla » Sun Jun 24, 2018 4:47 pm

[attachment=0]Association of Severe and therapy-refractory systematic lupus erthematosus and neuromyelitis Optica - a management challenge.pdf[/attachment]Association of severe and therapy-refractory systemic lupus erythematosus and neuromyelitis optica: a management challenge

Inês Furtado, Guiomar Pinheiro, Ana Campar, Teresa Mendonça


Systemic lupus erythematosus (SLE) is a multisystemic autoimmune disorder. Neuromyelitis optica (NMO)
is an infrequent neuro-inflammatory disorder, whose association with SLE remains rare. The authors report
the case of an 18-year-old woman, with SLE refractory to multiple immunosuppressive therapies and novel biological agents. Under immunosuppressive therapy, the patient presented with transverse myelitis with
contiguous spinal cord lesions and urinary incontinence, having been diagnosed with seropositive NMO, which was also proven to be refractory to common treatments. Partial recovery of the neurological deficits occurred with plasmapheresis, although not averting the brain involvement by NMO that ensued. The patient was listed nationally for allogeneic bone marrow transplant, but, unfortunately, no match was found and the patient died of severe cerebral NMO flare with coma due to brain swelling and consequent respiratory failure. Although the association of SLE and NMO is very rare, early diagnosis is crucial


Citation

Furtado I, Pinheiro G, Campar A, et al. BMJ Case Rep Published Online First:
please include Day Month Year]. doi:10.1136/bcr-2017- 222139
Attachments
Association of Severe and therapy-refractory systematic lupus erthematosus and neuromyelitis Optica - a management challenge.pdf
(412.07 KiB) Downloaded 4 times
Heather Sowalla

"Hope is being able to see that there is light despite all of the darkness."

+NMO AQP4
Preventative Treatment: Imuran (250mg) + Rituxan (2 Full Doses Every 3 Months)

Admin Teen & YA Support Group

Post Reply

Return to “NMO Library”